| Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation. | |
| | |
MedLine Citation:
|
PMID: 21820839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Paragangliomas are extremely rare neoplasms with multicentric presentation usually linked to familial tumor syndromes. This patient presented with the uncommon combination of concurrent bilateral carotid body tumors and a unilateral glomus jugulare mass that demonstrated vascular continuity. During treatment, the patient was found to be heterozygous for the SDHB germline mutation, an autosomal dominant genotype of the familial paraganglioma syndromes associated with increased malignancy. The unique profile of the SDHB patient as regards primary evaluation, surgical considerations, and extended surveillance was explored and has led to a proposed treatment algorithm for these patients. |
| | |
Authors:
|
Nicole Collins; Alan Dietzek |
Related Documents
:
|
11791109 - Acute retinal necrosis syndrome in a child. 21364519 - The implications and management of septic acute kidney injury. 22484069 - Posttraumatic benedikt's syndrome: a rare entity with unclear anatomopathological corre... 14570349 - Primary human immunodeficiency virus type 1 infection in a patient with acute rhabdomyo... 21180489 - Partial kluver-bucy syndrome as a delayed manifestation of head injury. 2253249 - Acute poststreptococcal glomerulonephritis and acute rheumatic fever: occurrence in the... 1777209 - Advances in ablation surgeries for dysrhythmias associated with wolff-parkinson-white s... 21116209 - Successful use of extracorporeal membrane oxygenation for ph1n1-induced refractory hypo... 10329909 - Illness and injury in animal confinement workers. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2011-08-06 |
Journal Detail:
|
Title: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Volume: 55 ISSN: 1097-6809 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2011-12-20 Completed Date: 2012-02-02 Revised Date: 2012-02-27 |
Medline Journal Info:
|
Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 216-9 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
Section of Vascular and Endovascular Surgery, Danbury Hospital, 41 Germantown Rd, Suite 101, Danbury, CT 06810, USA. [corrected]. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Carotid Body Tumor
/
enzymology,
genetics*,
pathology,
surgery DNA Mutational Analysis Genetic Predisposition to Disease Glomus Jugulare Tumor / enzymology, genetics*, pathology, surgery Heterozygote Humans Magnetic Resonance Imaging Male Middle Aged Mutation* Neoplasms, Multiple Primary* Phenotype Succinate Dehydrogenase / genetics* Tomography, X-Ray Computed Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
EC 1.3.5.1/SDHB protein, human; EC 1.3.99.1/Succinate Dehydrogenase |
| Comments/Corrections | |
Erratum In:
|
J Vasc Surg. 2012 Feb;55(2):627 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Abdominal aortic aneurysm and abdominal wall hernia as manifestations of a connective tissue disorde...
Next Document: Endovascular retrieval of a TrapEase permanent inferior vena cava filter from the aorta.