Document Detail


Contextual social cognition and the behavioral variant of frontotemporal dementia.
MedLine Citation:
PMID:  22529204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The significance of social situations is commonly context-embedded. Although the role of context has been extensively studied in basic sensory processing or simple stimulus-response settings, its relevance for social cognition is unknown. We propose the social context network model (SCNM), a fronto-insular-temporal network responsible for processing social contextual effects. The SCNM may 1) update the context and use it to make predictions, 2) coordinate internal and external milieus, and 3) consolidate context-target associative learning. We suggest the behavioral variant of frontotemporal dementia (bvFTD) as a specific disorder in which the reported deficits in social cognition (e.g., facial recognition, empathy, decision-making, figurative language, theory of mind) can be described as context impairments due to deficits in the SCNM. Disruption of orbitofrontal-amygdala circuit, as well as the frontal, temporal, and insular atrophy in bVFTD, suggests a relationship between context-sensitive social cognition and SCNM. In considering context as an intrinsic part of social cognition, we highlight the need for a situated cognition approach in social cognition research as opposed to an abstract, universal, and decontextualized approach. The assessment of context-dependent social cognition paradigms, the SCNM, and their possible application to neuropsychiatric disorders may provide new insight into bvFTD and other related frontal disorders.
Authors:
Agustin Ibañez; Facundo Manes
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Neurology     Volume:  78     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-24     Completed Date:  2012-07-20     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1354-62     Citation Subset:  AIM; IM    
Affiliation:
Institute of Cognitive Neurology and Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina. aibanez@ineco.org.ar
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MeSH Terms
Descriptor/Qualifier:
Animals
Cerebral Cortex / physiopathology*
Cognition Disorders / etiology*,  physiopathology*,  psychology
Cues*
Frontotemporal Dementia / complications*,  physiopathology*,  psychology
Humans
Neural Networks (Computer)
Social Behavior
Social Behavior Disorders / etiology*,  physiopathology
Comments/Corrections

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