Document Detail


Context processing performance in bipolar disorder patients.
MedLine Citation:
PMID:  17430297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Context processing is the adaptive control of current behavior through the use of prior context information. It has been found to be impaired in schizophrenia. Some studies have indicated that, compared with patients with schizophrenia, those with bipolar disorder (BPD) display a similar but less severe neuropsychological pattern of impairment. However, this cognitive dimension has not yet been examined in BPD patients in the existing literature. METHODS: An expectancy version of the AX continuous performance test (AX-CPT) was administered to 15 bipolar outpatients and 26 healthy controls. Patients with schizophrenia, in which context processing deficits are known to occur, were used as a reference group. RESULTS: Bipolar patients showed a context processing deficit relative to healthy controls, although this was less severe and generalized than in schizophrenia patients. CONCLUSIONS: These findings suggest there are milder impairments in context processing in BPD compared with schizophrenia. However, the severity of possible context processing deficits in BPD may have been underestimated in our sample of mostly euthymic outpatients.
Authors:
Paolo Brambilla; Angus W Macdonald; Roberto B Sassi; Melissa K Johnson; Alan G Mallinger; Cameron S Carter; Jair C Soares
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Bipolar disorders     Volume:  9     ISSN:  1398-5647     ISO Abbreviation:  Bipolar Disord     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-13     Completed Date:  2007-07-10     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  100883596     Medline TA:  Bipolar Disord     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  230-7     Citation Subset:  IM    
Affiliation:
Department of Pathology and Experimental and Clinical Medicine, Section of Psychiatry, University of Udine, Udine, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bipolar Disorder / epidemiology*
Cognition Disorders / diagnosis*,  epidemiology*
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Male
Mental Processes*
Neuropsychological Tests
Reaction Time*
Schizophrenia / epidemiology
Semantics*
Severity of Illness Index
Grant Support
ID/Acronym/Agency:
MH 01736/MH/NIMH NIH HHS; MH 068662/MH/NIMH NIH HHS; MH 068766/MH/NIMH NIH HHS; MH 30915/MH/NIMH NIH HHS; RR 020571/RR/NCRR NIH HHS

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