| Contested conceptions: PKU in the postwar discourse on reproduction. | |
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MedLine Citation:
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PMID: 14650403 Owner: HMD Status: MEDLINE |
Abstract/OtherAbstract:
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This essay uses the case of PKU as a portal through which to view shifting and contested views about genetics and reproductive behavior. In the early 1960s, the development of an effective therapy for PKU converged with the development of a test that could reliably detect the condition in newborns. As a result, infants born with the condition were enabled to reach adulthood and reproduce. However, by the early 1980s, a "second-generation" effect of screening was manifest, whereby many infants born to women who had been salvaged by screening were themselves severely damaged. In the 1940s, Lionel Penrose employed the case of PKU to demonstrate what was wrong with eugenics. Twenty years later, it would be used to illustrate why controls on reproduction were needed. |
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Authors:
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Diane B Paul |
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Publication Detail:
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Type: Historical Article; Journal Article |
Journal Detail:
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Title: Medicina nei secoli Volume: 14 ISSN: 0394-9001 ISO Abbreviation: Med Secoli Publication Date: 2002 |
Date Detail:
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Created Date: 2003-12-01 Completed Date: 2004-02-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0176472 Medline TA: Med Secoli Country: Italy |
Other Details:
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Languages: eng Pagination: 773-91 Citation Subset: Q |
Affiliation:
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Department of Political Science, University of Massachusetts, Boston, MA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Fertilization* Genetics / history* Great Britain History, 20th Century History, 21st Century Humans Phenylketonuria, Maternal / history* Pregnancy Reproductive Behavior / history* United States |
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