Document Detail


Contemporary strategy for aortic valve stenosis in octogenarians.
MedLine Citation:
PMID:  23851588     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The number of patients with aortic stenosis (AS) has been increasing over recent decades with the longer life expectancy of the general population. AS is life-threatening without surgery and since many elderly patients have a variety of comorbid conditions, 30-40 % of those with severe AS have been denied surgery. However, recent data on standard aortic valve replacement (AVR) for octogenarians have revealed excellent outcomes, with 2.4-6.8 % early mortality and similar survival rates of octogenarians who undergo AVR vs. the general population. The reported incidences of postoperative stroke, dialysis, and pacemaker implantation were 2.4, 2.6, and 4.6 %, respectively. Transcatheter aortic valve replacement (TAVR) is the alternative therapy for patients who are not able to undergo standard AVR and it is developing rapidly. The placement of aortic transcatheter valves (PARTNER) trial showed acceptable early outcomes. The mortality rates from any cause were 3.4 % in the TAVR group and 6.5 % in the AVR group at 30 days, 24.2 and 26.8 % at 1 year, and 33.9 and 35.0 % at 2 years, respectively. Stroke rate was higher in the TAVR group than in the AVR group (3.4 vs. 1.9 %). Vascular complications and paravalvular leakage are frequent procedure-related complications, which must be addressed because they are associated with increased mortality.
Authors:
Hiroyuki Tsukui; Kenji Yamazaki
Related Documents :
23921578 - Safety and effectiveness of microvascular decompression for the treatment of hemifacial...
17263998 - Elective treatment of abdominal aortic aneurysm with endovascular or open repair: the f...
17097898 - Visceral artery aneurysm: risk factor analysis and therapeutic opinion.
18509628 - Long-term results with matrix coils vs. gdc: an angiographic and histopathological comp...
11359388 - Pustular psoriasis of the nails: treatment and long-term follow-up of 46 patients.
7313338 - Different therapies and factors influencing response to therapy in idiopathic diffuse f...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-7-14
Journal Detail:
Title:  Surgery today     Volume:  -     ISSN:  1436-2813     ISO Abbreviation:  Surg. Today     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-7-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Cardiovascular Surgery, Tokyo Women's Medical University, 8-1 Kawada Shinjuku, Tokyo, 162-8666, Japan, htsukui@wf7.so-net.ne.jp.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Advances in Aptamer Screening and Small Molecule Aptasensors.
Next Document:  First experimental demonstration of an isotropic electromagnetic cloak with strict conformal mapping...