| Contemporary presentation and evolution of management of neck paragangliomas. | |
| | |
MedLine Citation:
|
PMID: 19497493 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: The aim of the present study was to review the contemporary presentation and evolution of management of neck paragangliomas. METHODS: Forty-one neck paragangliomas operated on in 36 patients over a 44 year period were included in the current report. The study period was divided into two parts, the first three decades (1964-1989), during which the current management techniques were evolved, and the last two decades (1990-2008). RESULTS: Patients presented with a palpable neck mass (n = 17), cranial nerve (CN) palsy (n = 3) or both (n = 6), or the lesion was an incidental finding (n = 14). The use of cross-section imaging modalities (n = 24) increased from 35% during the first part of the study to 95% during the second part of the study (P < .001). Preoperative embolization (introduced in 1979) was performed in 60% (median size 4.3 cm for embolized vs 3 cm [P = .02], for non-embolized tumors). During the first study period, the frequency of Shamblin group II/III tumors was 95% compared with a frequency of 42% during the second study period (P < .001, odds ratio 25), median blood loss was 600 ml and 150 ml, respectively (P = .001) and the transfusion rate was 44% and 5%, respectively (P = .008). The incidence of temporary and permanent new CN deficits postoperatively was 22.5% and 10%, respectively, and was similar during the two study periods. Three tumors were malignant, based on lymph node involvement (n = 1) or development of late metastases (n = 2). CONCLUSIONS: In the modern era, neck paragangliomas can be managed with a low incidence of long-term sequelae. Smaller, asymptomatic, and incidentally detected tumors are currently the most common presentation pattern. |
| | |
Authors:
|
Stavros K Kakkos; Daniel J Reddy; Alexander D Shepard; Judith C Lin; Timothy J Nypaver; Mitchell R Weaver |
Related Documents
:
|
7681273 - Angiogenesis induced by head and neck squamous cell carcinoma xenografts in the chick e... 3207313 - Congenital fibromatosis (myofibromatosis) of the orbit: a rare cause of proptosis at bi... 8306283 - Use of bremsstrahlung radiation to monitor y-90 tumor and whole body activities during ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Volume: 49 ISSN: 1097-6809 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-06-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 1365-73.e2 Citation Subset: IM |
Affiliation:
|
Division of Vascular Surgery, Department of Surgery, Henry Ford Hospital, Detroit, MI, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Meticulous blood pressure control is mandatory for symptomatic primitive trigeminal artery.
Next Document: Predictors of shunt during carotid endarterectomy with routine electroencephalography monitoring.