Document Detail

Contemporary coronary intervention in bifurcation lesions--two-year follow-up in an unselected cohort.
MedLine Citation:
PMID:  12218947     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Optimization of coronary angioplasty in bifurcation lesions remains a major challenge for percutaneous revascularization techniques. MATERIAL/METHODS: We evaluated procedural success, major in-hospital complications, target vessel revascularization, and 2-year clinical outcomes in 45 patients who underwent PTCA of a bifurcation lesion using currently available techniques and rigorous criteria for optimal immediate RESULTS: Angiographic success occurred in 100% of the parent vessels and in 84.4% of both vessels. Within the first 24 hours, there were no deaths or Q-wave myocardial infarction. Three non-Q-wave myocardial infarctions occurred (6.6%) and one emergency PTCA was necessary (2.2%). Therefore, clinical success was achieved in 91.2% of these patients. At 2-year follow-up, 3 cardiac deaths had occurred, the target revascularization rate was 20%, and the total frequency of major adverse cardiac events (MACE) was 37.8%. CONCLUSIONS: Optimization of coronary angioplasty in bifurcation lesions is possible and results in a high angiographic success rate, low risk of acute complications and acceptable long-term clinical outcomes. However, the fairly high incidence of MACE at 2 years suggests that bifurcation lesions remain a challenge in everyday practice despite contemporary intervention methods and the use of GPIIb/IIIa inhibitors.
Dariusz Dudek; Jacek Legutko; Paweł Zymek; Grzegorz L Kałuza; Jacek S Dubiel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  8     ISSN:  1234-1010     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-09     Completed Date:  2003-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  CR647-51     Citation Subset:  IM    
2nd Department of Cardiology, Institute of Cardiology, Jagiellonian University College of Medicine, Crakow, Poland.
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MeSH Terms
Angioplasty / methods*
Cohort Studies
Coronary Restenosis*
Coronary Vessels / injuries*
Follow-Up Studies
Middle Aged
Myocardial Revascularization
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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