| Contemporary coronary intervention in bifurcation lesions--two-year follow-up in an unselected cohort. | |
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MedLine Citation:
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PMID: 12218947 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Optimization of coronary angioplasty in bifurcation lesions remains a major challenge for percutaneous revascularization techniques. MATERIAL/METHODS: We evaluated procedural success, major in-hospital complications, target vessel revascularization, and 2-year clinical outcomes in 45 patients who underwent PTCA of a bifurcation lesion using currently available techniques and rigorous criteria for optimal immediate RESULTS: Angiographic success occurred in 100% of the parent vessels and in 84.4% of both vessels. Within the first 24 hours, there were no deaths or Q-wave myocardial infarction. Three non-Q-wave myocardial infarctions occurred (6.6%) and one emergency PTCA was necessary (2.2%). Therefore, clinical success was achieved in 91.2% of these patients. At 2-year follow-up, 3 cardiac deaths had occurred, the target revascularization rate was 20%, and the total frequency of major adverse cardiac events (MACE) was 37.8%. CONCLUSIONS: Optimization of coronary angioplasty in bifurcation lesions is possible and results in a high angiographic success rate, low risk of acute complications and acceptable long-term clinical outcomes. However, the fairly high incidence of MACE at 2 years suggests that bifurcation lesions remain a challenge in everyday practice despite contemporary intervention methods and the use of GPIIb/IIIa inhibitors. |
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Authors:
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Dariusz Dudek; Jacek Legutko; Paweł Zymek; Grzegorz L Kałuza; Jacek S Dubiel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 8 ISSN: 1234-1010 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-09 Completed Date: 2003-03-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
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Languages: eng Pagination: CR647-51 Citation Subset: IM |
Affiliation:
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2nd Department of Cardiology, Institute of Cardiology, Jagiellonian University College of Medicine, Crakow, Poland. mcdudek@cyf-kr.edu.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty / methods* Arteriosclerosis Cohort Studies Coronary Restenosis* Coronary Vessels / injuries* Female Follow-Up Studies Humans Male Middle Aged Myocardial Revascularization Time Factors Treatment Outcome |
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