Document Detail

Contemporary Non-Echo-planar Diffusion-weighted Imaging of Middle Ear Cholesteatomas.
MedLine Citation:
PMID:  22787002     Owner:  NLM     Status:  In-Data-Review    
Middle ear cholesteatoma is a common inflammatory disease that requires surgery due to potentially serious intracranial complications. Diagnosis of cholesteatoma is mainly clinical, with computed tomography (CT) used to evaluate disease extension before surgery. Certain patterns of bone erosion are specific, but CT attenuation does not allow differentiation from other inflammatory middle ear diseases. With its high tissue discrimination and contrast resolution, magnetic resonance imaging is valuable in diagnosis of cholesteatomas. Absent enhancement at delayed postcontrast imaging has been used for diagnosis. Diffusion-weighted imaging (DWI) is highly specific due to the high keratin content of cholesteatomas. New non-echo-planar DWI sequences, such as periodically rotated overlapping parallel lines with enhanced reconstruction, are superior to conventional echo-planar DWI, since they minimize susceptibility artifacts at the skull base and increase sensitivity for detection of lesions as small as 2 mm. This technique is indicated when clinical diagnosis is difficult and high tissue specificity is necessary, as in congenital, temporal bone, or atypical acquired middle ear cholesteatomas and residual or recurrent disease after surgery. Non-echo-planar DWI has been proposed for screening of postsurgical (residual or recurrent) cholesteatomas, thus obviating many second-look revision surgeries, especially after more conservative canal wall up surgery. © RSNA, 2012.
Fernando Más-Estellés; Manuel Mateos-Fernández; Blanca Carrascosa-Bisquert; Fernando Facal de Castro; Iciar Puchades-Román; Constantino Morera-Pérez
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  32     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1197-213     Citation Subset:  IM    
Departments of Radiology and ENT Surgery, Hospital Universitari í Politècnic La Fé de Valencia, Bulevar Sur s/n, 46026 Valencia, Spain.
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