Document Detail

Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: Time-course variation, influencing factors, and exposure assessment.
MedLine Citation:
PMID:  24112654     Owner:  NLM     Status:  Publisher    
Breast milk is a noninvasive specimen to assess maternal and infant exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In this study, 206 breast milk samples were collected from 87 participants during lactation, at <7, 15, 30, or 90days postpartum in four cities in Korea. The total concentrations of PCBs (ΣPCB) and OCPs (ΣOCP) ranged from <LOQ to 84.0 (median: 12.1) ngg(-1) lipid weight and from <LOQ to 559 (median: 144) ngg(-1) lipid weight, respectively. The residue levels of these contaminants measured in our study were relatively lower than those reported for European, African and Asian populations. Within a month postpartum typically after day seven the levels of ΣPCB and ΣOCP significantly increased. Some OCP compounds were correlated with maternal age, BMI, parity, and delivery mode. Certain types of dietary habits such as seafood and noodle consumption were significantly associated with ΣPCB and ΣOCP. The estimated daily intakes (EDIs) of ΣPCB and ΣOCP were 45.2-127ngkg(-1)bwday(-1) and 625-1259ngkg(-1)bwday(-1) during lactation, respectively, which are lower than the threshold values proposed by the US EPA and Health Canada. The exposure of Korean infants to chlordanes via breast milk had a potential health risk which deserves further investigation.
Sunggyu Lee; Sunmi Kim; Hyun-Kyung Lee; In-Seok Lee; Jeongim Park; Hai-Joong Kim; Jeong Jae Lee; Gyuyeon Choi; Sooran Choi; Sungjoo Kim; Su Young Kim; Kyungho Choi; Sungkyoon Kim; Hyo-Bang Moon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-7
Journal Detail:
Title:  Chemosphere     Volume:  -     ISSN:  1879-1298     ISO Abbreviation:  Chemosphere     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
College of Science and Technology, Hanyang University, Ansan, Republic of Korea.
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