Document Detail


Containment of a multiresistant Serratia marcescens outbreak.
MedLine Citation:
PMID:  9115604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 3-year-old male from Bolivia who sustained a full-thickness 80 per cent TBSA burn complicated by smoke inhalation on the 28 March 1995 was admitted to our burn centre on 6 April 1995. On 11 April the patient's wounds were colonized with a Serratia marcescens sensitive only to ciprofloxacin and imipenem. Sputum cultures revealed the same phenotypic S. marcescens. Two patients who were admitted days later had the same phenotypic S. marcescens. Their TBSA burns ranged from 54 to 80 per cent. Both were injured in early April. Sputum and wound cultures were also positive for S. marcescens. Precautionary measures were instituted immediately. All potential reservoirs were cultured. Cultures were negative for S. marcescens. Patient therapy was maintained via strict isolation. The first patient died on 17 May. The two remaining patients survived and were discharged colonized with S. marcescens. However, the biotype of the initial S. marcescens was different from the latter two. Early recognition of a multiresistant S. marcescens resulted in negating the spread of this agent to other patients.
Authors:
P Edgar; R Mlcak; M Desai; H A Linares; L G Phillips; J P Heggers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  23     ISSN:  0305-4179     ISO Abbreviation:  Burns     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-04-22     Completed Date:  1997-04-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  15-8     Citation Subset:  IM    
Affiliation:
Shriners Burns Institute, Galveston, Texas, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anti-Bacterial Agents / pharmacology
Burn Units
Burns / complications,  epidemiology*
Child
Child, Preschool
Cross Infection / complications,  epidemiology,  prevention & control
Disease Outbreaks / prevention & control*
Drug Resistance, Multiple*
Female
Humans
Male
Microbial Sensitivity Tests
Serratia Infections / complications,  epidemiology*,  prevention & control
Serratia marcescens / drug effects,  isolation & purification*
Survival Rate
Texas
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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