Document Detail

Contact sensitivity to lignocaine.
MedLine Citation:
PMID:  8403472     Owner:  NLM     Status:  MEDLINE    
Lignocaine is a rare contact allergen, in contrast to other local anaesthetics such as benzocaine, which commonly sensitize. The case of a patient sensitized to lignocaine through the use of a topical medication for the treatment of haemorrhoids is reported. Previous reports show that application of a lignocaine-containing preparation for pruritus ani is the most frequent cause of sensitization to lignocaine. The significance of sensitization to lignocaine is discussed in the light of its widespread use both in local anaesthesia and as an anti-arrhythmic.
S E Handfield-Jones; E Cronin
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  18     ISSN:  0307-6938     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1993-11-16     Completed Date:  1993-11-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  342-3     Citation Subset:  IM    
St John's Dermatology Centre, St Thomas' Hospital, London, UK.
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MeSH Terms
Administration, Topical
Dermatitis, Allergic Contact / etiology*
Lidocaine / administration & dosage,  adverse effects*
Middle Aged
Pruritus Ani / drug therapy
Reg. No./Substance:

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