| Contact Sensitization to the Allergens of European Baseline Series in Patients With Chronic Leg Ulcers. | |
| | |
MedLine Citation:
|
PMID: 22156607 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND AND OBJECTIVE. The pattern of contact sensitization among patients with chronic leg ulcers depends on the local practice of wound treatment along with demographic and clinical confounders. The study was aimed at revealing the associations between chronic leg ulcers and contact sensitization. MATERIAL AND METHODS. Between 2006 and 2008, 35 patients with chronic leg ulcers and surrounding dermatitis and 59 patients with contact dermatitis of the lower leg or foot were prospectively recruited at the Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences. Demographic and clinical data were collected in accordance with the "minimal data set" of the European Surveillance System on Contact Allergy. Patch testing was performed with the allergens of the European baseline series. RESULTS. At least one positive patch test reaction was found in 28 (80%) of the patients with chronic leg ulcers and in 24 (41%) of the patients with dermatitis of the lower leg or foot (P<0.001). Sensitization to some of the most common allergens, namely colophony, Myroxylon pereirae resin, and methyldibromo glutaronitrile, was prevalent in both the groups of patients, whereas sensitization to benzocaine, p-phenylenediamine, and lanolin alcohol was associated with the presence of chronic leg ulcers. Benzocaine was found to be the leading allergen among patients with chronic leg ulcers (positive patch test reactions in 34.4% of the patients). CONCLUSIONS. Contact sensitization to benzocaine, p-phenylenediamine, and lanolin is associated with the presence of chronic leg ulcers. |
| | |
Authors:
|
Aistė Beliauskienė; Skaidra Valiukevičienė; Brigita Sitkauskienė; Axel Schnuch; Wolfgang Uter |
Related Documents
:
|
9873847 - Inhibitor development and substitution therapy in a developing country: turkey. 22166627 - Prevalence of sensitivity to cockroach allergens and ige cross-reactivity between cockr... 8237997 - Hypofibrinolysis in patients with hypercoagulability: the roles of urokinase and of pla... 21535447 - Severe infusion reactions to infliximab: aetiology, immunogenicity and risk factors in ... 9227677 - Do chronic middle cerebral artery stenoses represent an embolic focus? a multirange tra... 11462117 - Mercury and nickel allergy: risk factors in fatigue and autoimmunity. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-5 |
Journal Detail:
|
Title: Medicina (Kaunas, Lithuania) Volume: 47 ISSN: 1648-9144 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9425208 Medline TA: Medicina (Kaunas) Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Skin and Venereal Diseases, Medical Academy, Lithuanian University of Health Sciences, Eivenių 2, 50028 Kaunas, Lithuania. aiste@asb.lt. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stroke Mortality Trends in the Population of Klaip?da From 1994 to 2008.
Next Document: Curcumins Promote Monocytic Gene Expression Related to ?-Amyloid and Superoxide Dismutase Clearance.