Document Detail

Contact-Force Recovery Can Predict Cardiac Perforation during Radiofrequency Ablation.
MedLine Citation:
PMID:  24797921     Owner:  NLM     Status:  Publisher    
BACKGROUND: During radiofrequency ablation (RFA), the ability to know whether a steam pop has led to cardiac perforation (CP) would be of profound clinical significance. We aimed to determine whether catheter contact-force characteristics can predict whether a steam pop during RFA causes CP.
METHODS: We used a 7.5F Thermocool® Smarttouch™ force-sensing catheter (Biosense Webster Inc., Diamond Bar, CA, USA) to perform open-chest left atrial RFA under direct visualization in four sheep. We measured the contact force and its direction every 50 ms during RFA. At each steam pop, we noted whether CP occurred. We then analyzed the contact-force signals to determine whether specific features predicted the presence (+) or absence (-) of CP.
RESULTS: A total of 24 steam pops occurred; 10 were CP+ and 14 were CP-. At the time of CP+ and CP- events, the contact force was 50 ± 25 and 40 ± 15 g, respectively (P = 0.146). All steam-pop events were associated with a rapid drop-off in contact force, but 10 of the 14 CP- events showed an immediate contact-force rebound, whereas none of the CP+ events did. This rebound presumably occurred as the catheter tip resumed contact with the left atrial wall. The average contact-force rebound equaled 80-100% of the contact-force drop-off.
CONCLUSIONS: The ability to measure catheter contact force during RFA is a valuable asset, as contact-force recovery may be used to predict CP. Further studies are warranted to validate our findings in the clinical setting.
Alireza Nazeri; Anand Ganapathy; Ali Massumi; Mehran Massumi; Garth Constantine; Shaul Raz; Mehdi Razavi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-4
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  -     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 Wiley Periodicals, Inc.
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