| Consumptive hypothyroidism: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 21382982 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Hepatic haemangioendothelioma is a rare vascular tumour in infants and may be associated with a unique form of thyroid function abnormalities. Hepatic haemangioendotheliomata is capable of producing an excess of the thyroid hormone inactivating enzyme, type 3 iodothyronine deiodinase. The increased enzyme activity leads to rapid degradation of thyroid hormones, resulting in frank hypothyroidism. We report a case of a three-month-old neonate with multiple hepatic haemangioendotheliomata and associated hypothyroidism. The patient required increasing doses of thyroid hormone. |
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Authors:
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N Jassam; T J Visser; T Brisco; D Bathia; P McClean; J H Barth |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-7 |
Journal Detail:
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Title: Annals of clinical biochemistry Volume: - ISSN: 1758-1001 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Clinical Biochemistry and Immunology, Leeds Teaching Hospitals Trust, Leeds LS1 3EX, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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