Document Detail


Consumption, supply and transport: self-organization without direct communication.
MedLine Citation:
PMID:  11539395     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
Swimming bacteria of the species Bacillus subtilis require and consume oxygen. In static liquid cultures the cells' swimming behaviour leads them to accumulate up oxygen concentration gradients generated by consumption and supply. Since the density of bacterial cells exceeds that of the fluid in which they live, fluid regions where cells have accumulated are denser than depleted regions. These density variations cause convection. The fluid motion is dynamically maintained by the swimming of the cells toward regions of attraction: the air-fluid interface and the fluctuating advecting attractors, gradients of oxygen concentration that are embedded in the convecting fluid. Because of the fluid dynamical conservation laws, these complex physical and biological factors generate patterns ordered over distances > 10000 bacterial cell diameters. The convection enhances long-range transport and mixing of oxygen, cells and extracellular products by orders of magnitude. Thus, through the interplay of physical and biological factors, a population of undifferentiated selfish cells creates functional dynamic patterns. Populations of bacteria that have organised themselves into regularly patterned regions of vigorous convection and varying cell concentration interact with their environment as if they were one purposeful, coherent multicellular individual. The mathematical and experimental ingredients of these remarkable phenomena are presented here.
Authors:
J O Kessler
Related Documents :
16217805 - Limitation of size by hypoxia in the fruit fly drosophila melanogaster.
19580395 - Mitochondrial regulation of cell survival and death during low-oxygen conditions.
18396305 - Contribution of reactive oxygen species to para-aminophenol toxicity in llc-pk1 cells.
20965425 - Cellular metabolic stress: considering how cells respond to nutrient excess.
17360445 - Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo.
18770655 - Cell counting.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Mathematics and computers in simulation     Volume:  40     ISSN:  0378-4754     ISO Abbreviation:  Math Comput Simul     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1997-07-22     Completed Date:  1997-07-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100971341     Medline TA:  Math Comput Simul     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  359-70     Citation Subset:  S    
Affiliation:
Physics Department, University of Arizona, Tucson 85721, USA. kessler@galileo.physics.arizona.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bacillus subtilis / physiology*
Biophysical Phenomena
Biophysics
Convection*
Gravitation
Locomotion / physiology*
Mathematics
Models, Biological
Oxygen Consumption / physiology*
Investigator
Investigator/Affiliation:
J O Kessler / U AZ, Tucson

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Middle and Late Cambrian sponge spicules from Hunan, China.
Next Document:  Vibration--rotation--tunneling dynamics calculations for the four-dimensional (HCl)2 system: a test...