Document Detail


Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in postmenopausal women.
MedLine Citation:
PMID:  10513764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to determine the relationship between the consumption of phosphoric acid-containing soft drinks and hypocalcemia in postmenopausal women. A case control study was designed to include 21 cases and 64 controls, matched by age and menopausal duration with similar family income, scholarship, and daily dietary intakes. Clinical and dietetic conditions that may produce hypocalcemia were considered as exclusion criteria. Cases were defined as a serum Ca level < or = 8.8 mg/dl, and controls as a serum CA level > 8.8 mg/dl. Women in the case group had a higher consumption of phosphoric acid-containing soft drink, and showed increased serum levels of PTH and hyperphosphaturia, than those in the control group without significant differences in 1,25(OH)2D3. In the multivariate regression analysis consumption of one or more bottles per day of cola soft drinks showed association with hypocalcemia (1.28, CI 95% 1.06-1.53). The consumption of soft drinks with phosphoric acid should be considered as an independent risk factor for hypocalcemia in postmenopausal women.
Authors:
G R Fernando; R M Martha; R Evangelina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical epidemiology     Volume:  52     ISSN:  0895-4356     ISO Abbreviation:  J Clin Epidemiol     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-10-21     Completed Date:  1999-10-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8801383     Medline TA:  J Clin Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1007-10     Citation Subset:  IM    
Affiliation:
Mexican Social Security Institute, Durango. guerrero@omanet.com.mx
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MeSH Terms
Descriptor/Qualifier:
Carbonated Beverages / adverse effects*
Case-Control Studies
Chi-Square Distribution
Female
Humans
Hypocalcemia / etiology*
Middle Aged
Phosphoric Acids / adverse effects*
Postmenopause*
Regression Analysis
Risk Factors
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Phosphoric Acids; 7664-38-2/phosphoric acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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