Document Detail


Consumption of dietary supplements containing Citrus aurantium (bitter orange)--2004 California Behavioral Risk Factor Surveillance Survey (BRFSS).
MedLine Citation:
PMID:  16968826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Following the marketing ban of ephedra-containing supplements in April 2004, many manufacturers substituted the herb Citrus aurantium for ephedra and marketed the products as "ephedra-free" supplements. Extracts of C. aurantium contain synephrine, a sympathomimetic alkaloid. OBJECTIVE: To determine the prevalence of consumption of dietary supplements containing C. aurantium in California during 2004. METHODS: We used the 2004 California Behavioral Risk Factor Surveillance Survey to determine the prevalence of consumption of dietary supplements containing C. aurantium in California during 2004. RESULTS: Two percent (n = 70) of the 4140 survey respondents reported taking a dietary supplement containing C. aurantium in the previous year. Reasons stated included energy enhancement, weight loss, and appetite suppression. Compared with nonusers, users were more likely to report being single, aged 18-34 years, and Hispanic; consuming 3 or more alcoholic drinks on days that they imbibed; and having a heavier body mass index. Among the 5 users who reported experiencing an adverse event that they attributed to the supplement, 3 indicated that the severity was mild. CONCLUSIONS: Given that supplements containing ephedra were banned in April 2004, the results from this study may serve as a baseline estimate against which future studies of the use of C. aurantium products may be compared.
Authors:
Karl C Klontz; Babgaleh B Timbo; Debra Street
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-09-12
Journal Detail:
Title:  The Annals of pharmacotherapy     Volume:  40     ISSN:  1542-6270     ISO Abbreviation:  Ann Pharmacother     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-27     Completed Date:  2006-11-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203131     Medline TA:  Ann Pharmacother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1747-51     Citation Subset:  IM    
Affiliation:
Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD 20740-3835, USA. karl.klontz@cfsan.fda.gov
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Appetite Regulation / drug effects
Behavioral Risk Factor Surveillance System*
California / epidemiology
Citrus* / adverse effects
Cross-Sectional Studies
Dietary Supplements* / adverse effects
Female
Humans
Male
Middle Aged
Risk Factors
Socioeconomic Factors
Weight Loss / drug effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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