| Consuming a small-moderate dose of red wine alone can alter the glucose-insulin relationship. | |
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MedLine Citation:
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PMID: 21164561 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The aim in the present study was to assess the effect of small-moderate red wine ingestion on the level of serum insulin and plasma glucose when nutritional status is varied. Twenty nondiabetic males (19-22 years) participated in the study. In the fasting trial, all participants underwent a 6 h fast prior to consuming 4 standard units of red wine (40 g alcohol) or the equivalent amount of placebo as dealcoholized wine (containing <0.5% alcohol, 0% resveratrol) over a 135 min period. Alternatively, in the feeding trial, participants consumed food for 45 min prior to ingesting 4 standard units of red wine (40 g alcohol) or placebo over 135 min. Serum insulin and plasma glucose were assessed at regular 45 min intervals during all trials. The results showed a significant decrease in the level of serum insulin and no significant change in plasma glucose concentration in the fasting trial. Alternatively, a significant alcohol-induced decrease in plasma glucose and no change in serum insulin occurred when red wine alone was consumed after food. It was concluded that red wine can alter the glucose-insulin relationship and ingesting red wine alone (without food) should not be encouraged in nondiabetic individuals. |
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Authors:
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Anna Kokavec; Mark A Halloran |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian journal of physiology and pharmacology Volume: 88 ISSN: 1205-7541 ISO Abbreviation: Can. J. Physiol. Pharmacol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372712 Medline TA: Can J Physiol Pharmacol Country: Canada |
Other Details:
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Languages: eng Pagination: 1147-56 Citation Subset: IM |
Affiliation:
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School of Psychological Science, La Trobe University, P.O. Box 199, Bendigo, Victoria 3552, Australia. A.Kokavec@latrobe.edu.au |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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