Document Detail


Consumer exposure to phthalates from paper packaging: an integrated approach.
MedLine Citation:
PMID:  20597021     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper presents an integrated approach to estimate the exposure of the Portuguese population to phthalates as a contaminant originating from paperboard packaging. The approach combined data of migrant concentration in the foods resulting from a stochastic simulation with consumption data of food packaged in paperboard. The results from the exposure model were validated with experimental values actually found in the food. A short surveillance exercise was conducted with samples collection from market shelves to identify and quantify the phthalates present in both the packages and the food. The distribution of values for the di-butyl phthalate concentration in the packages was used as the input of the initial concentration in the Weibull model to estimate the concentration of this phthalate in the foods. This distribution of occurrence data was then combined with the packaging usage data in a probabilistic simulation with a Monte Carlo sampling method. Exposure values ranged between zero and 8.95 microg day(-1) kg(bw), a value close to the tolerable daily intake established by the European Food Safety Authority (EFSA)--10 microg day(-1) kg(bw). However, the 97.5th percentile and the average were 1.82 and 0.44 day(-1) kg(bw), respectively, indicating that further refinement of the estimates is not necessary. Other phthalates were also detected in the packaging samples: di-isobutyl phthalate and di-ethylhexyl phthalate. The latter was present in all packaging samples collected and was detected in a few food samples at values requiring further investigation.
Authors:
M F Poças; J C Oliveira; J R Pereira; T Hogg
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  27     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-23     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  1451-9     Citation Subset:  IM    
Affiliation:
Packaging Department, Biotechnology College, Portuguese Catholic University, Porto, Portugal. mfpocas@esb.ucp.pt
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MeSH Terms
Descriptor/Qualifier:
Environmental Exposure / analysis
Food Contamination / analysis*
Food Packaging / instrumentation*
Humans
Monte Carlo Method
Paper*
Phthalic Acids / adverse effects*,  analysis*
Portugal
Reproducibility of Results
Chemical
Reg. No./Substance:
0/Phthalic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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