Document Detail

Construction of a tunable metallohydrolase center on an invertible molecular pocket.
MedLine Citation:
PMID:  21989979     Owner:  NLM     Status:  Publisher    
A trimer of cholic acid made by linking three cholic acid molecules with pentaerythritol via click chemistry serves as the center of an artificial metallohydrolase after the complexation of the triazole groups with a Zn(2+) ion. The invertible amphiphilic cavity can respond to the change in polarity of the solvent media and efficiently modulate the catalytic activity of the artificial enzyme.
Zhiming Zhang; Junqiu Liu; Quan Luo; Jiawei Zhang; Jiayun Xu; X X Zhu
Related Documents :
1417949 - Stereoselective conjugation of 2-bromocarboxylic acids and their urea derivatives by ra...
15999339 - Insecticidal and fungicidal activity of new synthesized chitosan derivatives.
17445829 - The structure of omci, a novel lipocalin inhibitor of the complement system.
9871589 - Synthesis of a new class of camptothecin derivatives, the long-chain fatty acid esters ...
11975529 - Diastereoselective synthesis and estimation of the conformational flexibility of 6-oxop...
3026489 - Transformation of 15-hydroperoxyeicosapentaenoic acid to lipoxin a5 and b5, mono- and d...
8691039 - Ascorbic acid is not clastogenic and does not modify the effect of extended low-dose-ra...
11509909 - Barrier function in reconstructed epidermis and its resemblance to native human skin.
8894299 - Sensory aspects of host location in mosquitoes.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-11
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  -     ISSN:  1477-0539     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, 130012, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hypothyroidism decreases proinsulin gene expression and the attachment of its mRNA and eEF1A protein...
Next Document:  Urea cycle disorders: brain MRI and neurological outcome.