Document Detail

Constrictive pericarditis.
MedLine Citation:
PMID:  18762706     Owner:  NLM     Status:  MEDLINE    
Constrictive pericarditis (CP) is characterized by scarring and loss of elasticity of the pericardium, resulting in external impedance of cardiac filling. In the developed world, CP is most frequently encountered as a consequence of previous cardiac surgery, thoracic irradiation, viral or idiopathic causes. Tuberculosis still remains a common cause of CP in the developing world, immigrants from underdeveloped nations, and immunosuppressed patients. Clinical signs and symptoms of right heart failure coupled with risk factors for pericardial disease should raise suspicion for CP. Echocardiographic evaluation and often cardiac catheterization are essential components of accurate diagnosis of CP. Enhanced interventricular dependence, with respiratory variation in the ventricular pressures, and ventricular discordance are the pathophysiologic hallmarks of CP. Imaging findings such as increased pericardial thickness or pericardial calcification on computed tomography can be supportive, but are not necessary for the diagnosis of CP. Pericardiectomy remains the most effective therapy for symptomatic CP.
Partho P Sengupta; Mackram F Eleid; Bijoy K Khandheria
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Publication Detail:
Type:  Journal Article     Date:  2008-09-02
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  72     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-26     Completed Date:  2008-12-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1555-62     Citation Subset:  IM    
Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ 85259, USA.
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MeSH Terms
Heart Catheterization
Magnetic Resonance Imaging
Pericarditis, Constrictive / diagnosis,  etiology,  physiopathology*
Ultrasonography, Doppler, Pulsed

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