Document Detail

Constitutive expression of c-myb mRNA in the adult rat brain.
MedLine Citation:
PMID:  11172765     Owner:  NLM     Status:  MEDLINE    
In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.
D H Shin; H W Lee; G S Jeon; H Y Lee; K H Lee; S S Cho
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain research     Volume:  892     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  203-7     Citation Subset:  IM    
Department of Anatomy, Dankook University College of Medicine, Chonan, South Korea.
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MeSH Terms
Brain / physiology*
Genes, myb*
Neurons / physiology
Organ Specificity
Prosencephalon / physiology
Proto-Oncogene Proteins c-myb / genetics*
RNA, Messenger / analysis
Rats, Sprague-Dawley
Superior Colliculi / physiology
Transcription, Genetic*
Reg. No./Substance:
0/Proto-Oncogene Proteins c-myb; 0/RNA, Messenger

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