Document Detail

Constipation: evaluation and treatment of colonic and anorectal motility disorders.
MedLine Citation:
PMID:  17950444     Owner:  NLM     Status:  MEDLINE    
This article focuses on the colonic and anorectal motility disturbances that are associated with chronic constipation and their management. Functional chronic constipation consists of three overlapping subtypes: slow transit constipation, dyssynergic defecation, and irritable bowel syndrome with constipation. The Rome criteria may serve as a useful guide for making a clinical diagnosis of functional constipation. Today, an evidence-based approach can be used to treat patients with chronic constipation. The availability of specific drugs for the treatment of chronic constipation, such as tegaserod and lubiprostone, has enhanced the therapeutic armamentarium for managing these patients. Randomized controlled trials have also established the efficacy of biofeedback therapy in the treatment of dyssynergic defecation.
Satish S C Rao
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Gastroenterology clinics of North America     Volume:  36     ISSN:  0889-8553     ISO Abbreviation:  Gastroenterol. Clin. North Am.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-22     Completed Date:  2008-01-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706257     Medline TA:  Gastroenterol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  687-711, x     Citation Subset:  IM    
Division of Gastroenterology & Hepatology, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
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MeSH Terms
Constipation* / diagnosis,  physiopathology,  therapy
Diagnostic Techniques, Digestive System
Dietary Fiber / therapeutic use*
Evidence-Based Medicine / methods*
Exercise Therapy / methods*
Gastrointestinal Transit / physiology
Laxatives / therapeutic use*
Grant Support
Reg. No./Substance:

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