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Consistency of Myocardial Mass Computations as a Quality Control Check on Rest and Stress Left Ventricular Ejection Fractions Computed From 82Rb PET Data.
MedLine Citation:
PMID:  24873785     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: Changes in left ventricular (LV) ejection fraction (EF) seen in gated Rb data are of interest because the heart is in a genuinely different physiologic state during stress than at rest. A measure that validates internal consistency of LV EF data would be highly desirable. Left ventricular mass calculations are performed simultaneously with EF determinations, requiring similar operator choices, and although LV volumes may change from rest to stress, mass values should be constant. Constancy of LV mass calculations could provide a useful internal check on the consistency of LV EF computations.
PATIENTS AND METHODS: We retrospectively reviewed data for 205 patients referred for evaluation of known or suspected coronary disease who had rest and regadenoson stress gated Rb PET/CT myocardial perfusion imaging. Equilibrium gated myocardial perfusion PET data were analyzed to calculate LV volumes, EF, and simultaneously mass values.
RESULTS: Rest mass ranged from 62 to 284 g (median, 115 g), stress mass from 39 to 315 g (median, 120 g), and differences were -25 to +25 g (median, 1 g). Rest and stress mass values were statistically similar (121 ± 37 g vs 124 ± 49 g, P = 0.45) and correlated strongly with one another (r = 0.94, P < 0.0001).
CONCLUSIONS: Left ventricular mass calculations are constant from rest to stress over a wide range of ventricular volumes and ejection fractions. Consistency of LV mass values can serve as confirmation of the appropriateness of operator choices when LV EF calculations are performed.
Authors:
Andrew Van Tosh; Nathaniel Reichek; Barbara Phippen-Nater; Christopher J Palestro; Kenneth J Nichols
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-28
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  -     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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