Document Detail


Considerations in evaluating human spermatogenesis on the basis of total sperm per ejaculate.
MedLine Citation:
PMID:  19443909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Total number of sperm per ejaculate (TSperm) is an important measure for clinicians to provide advice to patient couples. However, TSperm per hour of abstinence (TSperm/h) is a better measure for epidemiologist-andrologist teams or clinicians to evaluate spermatogenesis because it is a rate function. This review looks at the interplay and impacts of rate of sperm accumulation in the excurrent duct system, abstinence interval, sexual arousal, and masturbation vs intercourse on observed TSperm. It also examines why and when TSperm/h might provide a meaningful quantitative evaluation of spermatogenesis (ie, rate of sperm production). There is no doubt that TSperm increases with longer abstinence, and in different men plateaus after 2-9 days. Clinicians wishing to maximize number of fully functional sperm available during intercourse, or for artificial insemination, might wish to recommend 6-7 days of abstinence. Diagnostically, the important feature is TSperm/h. After abstinence interval exceeds 64-72 hours, TSperm/h has started to decline in most nonoligozoospermic men as rate of sperm accumulation in the excurrent ducts approaches zero; apparently increasingly more sperm are voided in urine. Clinicians or epidemiologist-andrologist teams wishing to have optimal distinction among individuals with high, typical, or low sperm production (ie, normal or abnormal spermatogenesis) should accurately measure TSperm/h for samples provided after 42-54 hours' abstinence (never <or=36 or >64 hours). Longer abstinence intervals reward men with poor sperm production, because sperm accumulate in the excurrent ducts for 7 days or more of abstinence, and penalize men with good sperm production, because after 3 days or less of abstinence their excurrent ducts probably are full.
Authors:
Rupert P Amann
Related Documents :
8331289 - Flow cytometric sorting of living, highly motile human spermatozoa based on evaluation ...
9973139 - Influence of sperm plasma membrane destruction on human sperm head decondensation and p...
17087909 - Sex ratio of early embryos fertilized in vitro with spermatozoa separated by percoll.
6723869 - The use of retrograde transport of horseradish peroxidase for studying the dendritic tr...
18781079 - Effect of high haematocrit on the efficiency of high-flux dialysis therapies.
2275479 - Species attribution of the swartkrans member 1 first metacarpals: sk84 and skx 5020.
20884219 - Outcomes of ventricular assist device support in young patients with small body surface...
1848289 - Computerized densitometric analysis of interproximal bone levels in a controlled clinic...
2335529 - Mechanical properties of cranial sutures.
Publication Detail:
Type:  Journal Article; Review     Date:  2009-05-14
Journal Detail:
Title:  Journal of andrology     Volume:  30     ISSN:  1939-4640     ISO Abbreviation:  J. Androl.     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-10-21     Completed Date:  2010-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106453     Medline TA:  J Androl     Country:  United States    
Other Details:
Languages:  eng     Pagination:  626-41     Citation Subset:  IM    
Affiliation:
Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, Colorado, USA. rpalra62@comcast.net
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Coitus
Ejaculation
Epididymis / cytology,  physiology
Humans
Infertility, Male / etiology,  therapy
Male
Masturbation
Semen / cytology*
Sexual Abstinence
Sperm Count*
Spermatogenesis / physiology*
Spermatozoa
Testicular Diseases / complications
Time Factors
Vas Deferens / cytology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Total sperm per ejaculate of men: obtaining a meaningful value or a mean value with appropriate prec...
Next Document:  Angiotensin-converting enzyme and adducin-1 polymorphisms in women with preeclampsia and gestational...