Document Detail

Conservative treatment of postsurgical lymphatic leaks with somatostatin-14.
MedLine Citation:
PMID:  10713026     Owner:  NLM     Status:  MEDLINE    
Successful management of lymphatic leaks by continuous IV administration of somatostatin was first reported by Ulibarri and coworkers in Spain,(1) and more recently by authors from Italy(2) and Switzerland.(3) The present article reports the clinical history of two patients in whom postsurgical lymphatic leak was successfully treated after the administration of either somatostatin-14 alone (case 1) or combined somatostatin-14 and total parenteral nutrition (TPN; case 2). Although further pathophysiologic studies are needed for the elucidation of its mechanisms of action, somatostatin-14 seems to be an intriguing therapy against postsurgical lymphatic leaks that may make potentially risky transthoracic reoperation unnecessary.
J M Collard; P F Laterre; F Boemer; M Reynaert; R Ponlot
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  117     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-04-04     Completed Date:  2000-04-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  902-5     Citation Subset:  AIM; IM    
Departments of Surgery, St-Luc Academic Hospital, Brussels, Belgium.
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MeSH Terms
Combined Modality Therapy
Fistula / drug therapy*
Infusions, Intravenous
Middle Aged
Postoperative Complications / drug therapy*
Somatostatin / administration & dosage*
Surgical Instruments
Thoracic Duct / injuries*,  surgery
Reg. No./Substance:

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