| Conservative management of extra-adrenal pheochromocytoma during pregnancy. | |
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MedLine Citation:
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PMID: 15863575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Extra-adrenal pheochromocytomas are catecholamine-secreting tumors that arise from chromaffin cells of the paraganglion sympathetic system. All of the previously reported cases have described surgical resection during the antepartum period. CASE: At 14 weeks of gestation, a multiparous patient was diagnosed with an extra-adrenal dopaminergic pheochromocytoma. A decision was made to delay surgical intervention until the postpartum period. Phenoxybenzamine, 10 mg per day, was subsequently started. At 35 + 2 weeks of gestation, the patient delivered a 2,600 g infant via an uncomplicated cesarean. Three weeks later, the extra-adrenal pheochromocytoma was removed, and she also underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and rectosigmoid resection with end-to-end colostomy. CONCLUSION: Conservative management of dopaminergic-secreting extra-adrenal pheochromocytomas can result in favorable maternal and fetal outcomes. |
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Authors:
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Caela Miller; Victor Bernet; John C Elkas; Louis Dainty; Robert B Gherman |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 105 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-05-02 Completed Date: 2005-06-30 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1185-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Division of Maternal/Fetal Medicine, National Naval Medical Center, Bethesda, Maryland 20889, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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diagnosis,
drug therapy* Adrenalectomy / methods Adult Biopsy, Needle Cesarean Section Dose-Response Relationship, Drug Drug Administration Schedule Female Follow-Up Studies Gestational Age Humans Immunohistochemistry Phenoxybenzamine / therapeutic use* Pheochromocytoma / diagnosis, drug therapy* Postpartum Period Pregnancy Pregnancy Complications, Neoplastic / diagnosis, drug therapy* Pregnancy Outcome* Risk Assessment Tomography, X-Ray Computed Treatment Outcome Ultrasonography, Prenatal |
| Chemical | |
Reg. No./Substance:
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59-96-1/Phenoxybenzamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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