| Conservation surgery for T2 and T3 carcinomas of the supraglottic larynx. | |
| | |
MedLine Citation:
|
PMID: 3348897 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The treatment of choice for supraglottic carcinomas of intermediate size (stages T2 and T3) remains controversial. Between 1974 and 1983 in our institution, 139 patients with supraglottic carcinoma of intermediate size were judged retrospectively to have been technically amenable to conservation surgery. Primary disease control at three years was achieved in 100% of the patients treated by supraglottic laryngectomy, 91% (34 patients) of those treated by total laryngectomy, and 69% (81 patients) of those treated by radiotherapy. Of the latter group, 62% were salvaged by total laryngectomy yielding a net three-year local control of 85%. Determinate five-year survival rates were 89% for supraglottic laryngectomy, 78% for total laryngectomy, and 70% for radiotherapy. Significant problems with aspiration occurred in four patients (16%) who were treated by conservation surgery, and two patients (8%) required a permanent tracheostomy. The results of this study show that supraglottic laryngectomy with postoperative radiotherapy as indicated is a highly effective method for the local control of supraglottic carcinoma of intermediate size that is amenable to conservation surgery. |
| | |
Authors:
|
K T Robbins; W Davidson; L J Peters; H Goepfert |
Related Documents
:
|
11859977 - Treatment outcome after laser excision of early glottic squamous cell carcinoma--a lite... 23006447 - A randomized, phase 2 study comparing pemetrexed plus best supportive care versus best ... 19932447 - Photofrin pdt for early stage oesophageal cancer: long term results in 40 patients and ... 19260127 - Higher laryngeal preservation rate after co2 laser surgery compared with radiotherapy i... 15120937 - Meta-analysis of autologous bone marrow transplantation versus chemotherapy in adult pa... 23469977 - Repetitive chemoembolization of hypovascular liver metastases from the most common prim... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Archives of otolaryngology--head & neck surgery Volume: 114 ISSN: 0886-4470 ISO Abbreviation: Arch. Otolaryngol. Head Neck Surg. Publication Date: 1988 Apr |
Date Detail:
|
Created Date: 1988-04-27 Completed Date: 1988-04-27 Revised Date: 2006-03-28 |
Medline Journal Info:
|
Nlm Unique ID: 8603209 Medline TA: Arch Otolaryngol Head Neck Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 421-6 Citation Subset: AIM; IM |
Affiliation:
|
Department of Head and Neck Surgery, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Female Glottis Humans Laryngeal Neoplasms / mortality, radiotherapy, surgery* Laryngectomy Male Middle Aged Neoplasm Recurrence, Local Neoplasm Staging Pneumonia, Aspiration / etiology Postoperative Complications Retrospective Studies Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Rinne test for conductive deafness. A critical reappraisal.
Next Document: Radiosensitivity of head and neck cancer cells in vitro. A 96-well plate clonogenic cell assay for s...