Document Detail

Conservation of bactericidal activity in ultrasound-exposed murine peritoneal phagocytic cells.
MedLine Citation:
PMID:  1413271     Owner:  NLM     Status:  MEDLINE    
Murine peritoneal exudate cells (PEC), predominantly macrophages, were insonated in vitro with burst-mode ultrasound and assayed for their ability to phagocytose and kill Staphylococcus aureus. PEC were exposed at 37 degrees C in rotating tubes to 1-MHz, burst-mode (10 ms on, 10 ms off) ultrasound at 3.7 +/- 0.2 W/cm2 ISPTA (7.4 +/- 0.4 W/cm2 ISPBA) for 150 s. Bactericidal activity was assayed at 1, 2, and 3 h after exposure and subsequent 37 degrees C incubation with the bacteria for 20 min. In these experiments, which comprised 17 treated and 7 sham-treated control samples, there was no significant difference in results between treated and control samples (p > 0.29).
S S Prohaska; V G Rimer; D Tusé; G T Pryor; P D Edmonds
Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  18     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  1992  
Date Detail:
Created Date:  1992-11-25     Completed Date:  1992-11-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  601-6     Citation Subset:  IM    
Cell and Molecular Biology Laboratory, SRI International, Menlo Park, CA 94025.
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MeSH Terms
Mice, Inbred Strains
Peritoneal Cavity / cytology*
Phagocytes / physiology*
Staphylococcus aureus*
Grant Support

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