Document Detail


Consensus workshop on the toxic effects of long-term PUVA therapy.
MedLine Citation:
PMID:  9606329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The possibility that there is an increased risk of melanoma in patients with psoriasis treated with psoralen-UV-A (PUVA) therapy has raised concern on the part of physicians and patients about the long-term safety of this treatment. In response to this concern, the National Psoriasis Foundation sponsored a workshop at which invited participants with expertise in PUVA therapy, psoriasis treatment, melanoma and nonmelanoma skin cancer, and epidemiological and clinical trials were asked to develop a consensus on the following 3 issues: the risk of long-term adverse effects of PUVA therapy with emphasis on nonmelanoma and melanoma skin cancer; the guidelines for physicians and patients for selection and use of PUVA therapy with consideration of the risk-benefit ratio of this treatment compared with the risk-benefit ratios of alternative treatments; and the directions for further evaluation of the long-term effects Of PUVA therapy.
Authors:
W L Morison; R D Baughman; R M Day; P D Forbes; H Hoenigsmann; G G Krueger; M Lebwohl; R Lew; L Naldi; J A Parrish; M Piepkorn; R S Stern; G D Weinstein; S E Whitmore
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Publication Detail:
Type:  Consensus Development Conference; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Archives of dermatology     Volume:  134     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-06-18     Completed Date:  1998-06-18     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  595-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Melanoma / chemically induced*
PUVA Therapy / adverse effects*
Psoriasis / drug therapy
Risk
Skin Neoplasms / chemically induced*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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