Document Detail

Consensus recommendations for transcranial color-coded duplex sonography for the assessment of intracranial arteries in clinical trials on acute stroke.
MedLine Citation:
PMID:  19661474     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Transcranial color-coded duplex sonography has become a standard diagnostic technique to assess the intracranial arterial status in acute stroke. It is increasingly used for the evaluation of prognosis and the success of revascularization in multicenter trials. The aim of this international consensus procedure was to develop recommendations on the methodology and documentation to be used for assessment of intracranial occlusion and for monitoring of recanalization. METHODS: Thirty-five experts participated in the consensus process. The presented recommendations were approved during a meeting of the consensus group in October 2008 in Giessen, Germany. The project was an initiative of the German Competence Network Stroke and performed under the auspices of the Neurosonology Research Group of the World Federation of Neurology. RESULTS: Recommendations are given on how examinations should be performed in the time-limited situation of acute stroke, including criteria to assess the quality of the acoustic bone window, the use of echo contrast agents, and the evaluation of intracranial vessel status. The important issues of the examiners' training and experience, the documentation, and analysis of study results are addressed. One central aspect was the development of standardized criteria for diagnosis of arterial occlusion. A transcranial color-coded duplex sonography recanalization score based on objective hemodynamic criteria is introduced (consensus on grading intracranial flow obstruction [COGIF] score). CONCLUSIONS: This work presents consensus statements in an attempt to standardize the application of transcranial color-coded duplex sonography in the setting of acute stroke research, aiming to improve the reliability and reproducibility of the results of future stroke studies.
Max Nedelmann; Erwin Stolz; Tibo Gerriets; Ralf W Baumgartner; Giovanni Malferrari; Guenter Seidel; Manfred Kaps;
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Publication Detail:
Type:  Consensus Development Conference; Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't     Date:  2009-08-06
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  40     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-28     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3238-44     Citation Subset:  IM    
Department of Neurology, Justus Liebig University, Giessen, Germany.
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MeSH Terms
Brain Ischemia / pathology,  physiopathology,  ultrasonography
Cerebral Arteries / pathology,  physiopathology,  ultrasonography*
Cerebrovascular Circulation / physiology
Clinical Trials as Topic / methods*,  standards*
Disease Progression
Predictive Value of Tests
Reproducibility of Results
Severity of Illness Index
Stroke / pathology,  physiopathology,  ultrasonography*
Ultrasonography, Doppler, Transcranial / methods*,  standards*
Anita Arsovska / ; Eva Bartels / ; Ralf Baumgartner / ; Dirk Droste / ; Juergen Eggers / ; Jens Eyding / ; Georg Gahn / ; Dimitrios Georgiadis / ; Tibo Gerriets / ; Michael Goertler / ; Hajo Hamer / ; Arjan W Hoksbergen / ; Manfred Kaps / ; Christof Kloetzsch / ; Grzegorz Kozera / ; Jaroslaw Krejza / ; Vincent Larrue / ; Giovanni Malferrari / ; Mathias Maeurer / ; Kazuo Minematsu / ; Max Nedelmann / ; Fabienne Perren / ; Thomas Postert / ; E Bernd Ringelstein / ; Martin Ritter / ; Felix Schlachetzki / ; Eberhard Schmitt / ; Guenter Seidel / ; David Skoloudik / ; Erwin Stolz / ; Roman Sztajzel / ; Charles Tegeler / ; Gerhard-Michael von Reutern / ; Joanna Wardlaw / ; Michael Wunderlich /

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