Document Detail

Conjugated fatty acids in food and their health benefits.
MedLine Citation:
PMID:  16198256     Owner:  NLM     Status:  MEDLINE    
Conjugated fatty acids (CFAs) are a mixture of positional and geometric isomers of polyunsaturated fatty acids with conjugated double bonds. Reports indicate that CFAs have potent beneficial effects, including antitumor, antiobese, antiatherogenic and antidiabetic activities. The molecules have also been shown to prevent the onset of hypertension. Recent reports suggest that each CFA isomer has different functions, for example the 10trans,12cis isomer of conjugated linoleic acid (CLA) has anticarcinogenic, antiobese and antidiabetic effects, whereas the 9cis,11trans-CLA isomer exerts an anticancer effect. Although it would be interesting to know the effects of CFAs on humans, there are only few reports concerning the anticancer and antiobese effects of CLA in humans. More detailed evaluations of the physiological bioactivities of CFA isomers on lifestyle-related diseases in humans and animals will be of great interest in future studies.
Koji Nagao; Teruyoshi Yanagita
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of bioscience and bioengineering     Volume:  100     ISSN:  1389-1723     ISO Abbreviation:  J. Biosci. Bioeng.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-10-03     Completed Date:  2005-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888800     Medline TA:  J Biosci Bioeng     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  152-7     Citation Subset:  IM    
Laboratory of Nutrition Biochemistry, Department of Applied Biological Sciences, Saga University, 1 Honjo, Saga 840-8502, Japan.
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MeSH Terms
Anti-Obesity Agents / administration & dosage
Anticarcinogenic Agents / administration & dosage
Antilipemic Agents / administration & dosage
Fatty Acids / administration & dosage*
Reg. No./Substance:
0/Anti-Obesity Agents; 0/Anticarcinogenic Agents; 0/Antilipemic Agents; 0/Fatty Acids

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