| Conjugated catecholamines in rats transfused with perfluorocarbon blood substitute. | |
| | |
MedLine Citation:
|
PMID: 4094719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The reappearance of circulating catecholamines (CAs) after transfusion with perfluorocarbon blood substitute and the importance of blood for CA conjugation were determined in rats. Arterial plasma concentrations of unconjugated (i.e. free), sulfoconjugated and glucuronoconjugated forms of the CAs dopamine (DA), noradrenaline (NA) and adrenaline (AD) in cannulated, anesthetized, control rats remained stable during the 4.5 h long experiments. Contrarily, in parallel experiments with another group of rats, replacement of blood by the perfluorocarbon blood substitute initially lowered the arterial concentrations of DA glucuronide, free AD and AD glucuronide; subsequently, free DA, NA and AD increased, followed by delayed increases in conjugated CA levels. These changes in CA concentrations preceded a fall in systemic arterial blood pressure (pa) and thus were not the consequences of hypotension. |
| | |
Authors:
|
J X Wilson; N H West; M Amies; E Michalska |
Related Documents
:
|
9389209 - Changes of cholinesterase activity in the erythrocytes, plasma, diaphragm, liver and va... 942629 - A case of blood-illness-injury phobia treated behaviorally. 3409999 - Non-invasive monitoring of ionic current flow during development by squid magnetometry. 12405719 - Eiph: postrace endoscopic evaluation of standardbreds and thoroughbreds. 20051059 - Is "transfusion-associated necrotizing enterocolitis" an authentic pathogenic entity? 3415469 - The risk of splenorrhaphy. 14630989 - Coronary flow reserve in the newborn lamb: an intracoronary doppler guide wire study. 2504939 - Toxicity in a case of acute and massive overdose of chlordiazepoxide and its correlatio... 18293819 - What is optimal flow and how to validate this. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Neuroscience letters Volume: 62 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 1985 Dec |
Date Detail:
|
Created Date: 1986-04-21 Completed Date: 1986-04-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 329-33 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Substitutes / administration & dosage* Blood Transfusion* / methods Catecholamines / blood* Dopamine / blood Epinephrine / blood Fluorocarbons / administration & dosage* Glucuronates / blood Male Norepinephrine / blood Rats Rats, Inbred Strains Sulfates / blood |
| Chemical | |
Reg. No./Substance:
|
0/Blood Substitutes; 0/Catecholamines; 0/Fluorocarbons; 0/Glucuronates; 0/Sulfates; 311-89-7/perfluorotributylamine; 51-41-2/Norepinephrine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neonatal exposure to naltrexone affects morphine sensitivity and facilitates sexual behaviour in fem...
Next Document: Pulmonary edema as a cause for fulminant death following microinjection of kainic acid into the rat ...