Document Detail

Conjugated polyelectrolyte capsules: light-activated antimicrobial micro "Roach Motels".
MedLine Citation:
PMID:  20355752     Owner:  NLM     Status:  MEDLINE    
Microcapsules consisting of alternating layers of oppositely charged poly(phenylene ethynylene)-type conjugated polyelectrolytes (CPEs) were prepared via layer-by-layer deposition onto MnCO3 template particles followed by dissolution of the template particles using an ethylenediaminetetraacetate solution. The resulting microcapsules exhibit bright-green fluorescence emission characteristics of the CPEs. Strong antimicrobial activity was observed upon mixing of polyelectrolyte capsules with Cobetia marina or Pseudomonas aeruginosa followed by white-light irradiation. It was demonstrated that the materials act as highly effective light-activated micro "Roach Motels" with greater than 95% kill after exposure to approximately 1 h of white light.
Thomas S Corbitt; Jonathan R Sommer; Sireesha Chemburu; Katsu Ogawa; Linnea K Ista; Gabriel P Lopez; David G Whitten; Kirk S Schanze
Publication Detail:
Type:  Letter; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  ACS applied materials & interfaces     Volume:  1     ISSN:  1944-8244     ISO Abbreviation:  ACS Appl Mater Interfaces     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2010-04-01     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101504991     Medline TA:  ACS Appl Mater Interfaces     Country:  United States    
Other Details:
Languages:  eng     Pagination:  48-52     Citation Subset:  IM    
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MeSH Terms
Alkynes / chemistry
Disinfectants / chemistry*,  pharmacology,  radiation effects
Electrolytes / chemistry
Ethers / chemistry
Microscopy, Confocal
Microscopy, Fluorescence
Microtechnology / methods*
Oceanospirillaceae / drug effects
Photochemical Processes
Polymers / chemistry*
Pseudomonas aeruginosa / drug effects
Reg. No./Substance:
0/Alkynes; 0/Disinfectants; 0/Electrolytes; 0/Ethers; 0/Polymers; 0/phenyleneethynylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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