Document Detail

Conjuctivitis and keratoconjunctivitis associated with primary immunodeficiency diseases.
MedLine Citation:
PMID:  333923     Owner:  NLM     Status:  MEDLINE    
Nineteen patients with a variety of well-defined primary immunodeficiency diseases were examined for ocular abnormalities. Eight patients with low levels, or absence, of all the major serum immunoglobulins had conjunctivitis or keratoconjunctivitis associated with bacterial infection. The remaining 11 patients, who had at least one immunoglobulin class present in normal concentration in the serum, showed no inflammatory ocular lesion. Absence of only IgA, the major tear immunoglobulin, did not predispose the eye to these lesions.
R M Franklin; J A Winkelstein; D S Seto
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  84     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  563-6     Citation Subset:  AIM; IM    
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MeSH Terms
Agammaglobulinemia / complications*
Bacterial Infections / complications
Clinical Trials as Topic
Conjunctivitis / complications*
Dysgammaglobulinemia / complications*
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Immunoglobulins / analysis
Immunologic Techniques
Keratoconjunctivitis / complications*
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulins

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