Document Detail

Conjoined twins after intracytoplasmic sperm injection and transfer of a single day 2 embryo: case report.
MedLine Citation:
PMID:  19878939     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe a case of conjoined twins after intracytoplasmic sperm injection (ICSI) and transfer of a single day 2 embryo. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 30-year-old woman underwent ICSI with a transfer of a single day 2 embryo. INTERVENTION(S): Vaginal ultrasound examination was performed during early pregnancy. RESULT(S): The diagnosis of conjoined twins was made by vaginal ultrasonography at 9 weeks' gestation. The conjoined fetuses were diagnosed as thoracopagus twins with a single beating heart shared between the thoraxes. Extensive ultrasound examination suggested an extremely poor prognosis, Therapeutic termination was performed at 11 weeks. CONCLUSION(S): Given that single embryo transfers are able to shed light on the real incidence of conjoined twins developed on day 2/3 or on day 5/6, this is of interest mechanistically. Thus, it should be taken into account when trying to determine the true incidence of conjoined twins and ultimately trying to understand why these anomalies occur. The importance of early expert vaginal ultrasonography in pregnancies resulting from assisted reproductive technologies is emphasized.
Helene Poret; Milene Blanchard; Malak Lemseffer; Dominique Royere; Fabrice Guerif
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Publication Detail:
Type:  Journal Article     Date:  2009-10-29
Journal Detail:
Title:  Fertility and sterility     Volume:  93     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  268.e7-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Service de M?decine et Biologie de la Reproduction, CHRU Bretonneau, Tours, France.
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MeSH Terms
Abortion, Therapeutic
Early Diagnosis
Embryo Transfer / adverse effects*
Gestational Age
Sperm Injections, Intracytoplasmic / adverse effects*
Treatment Outcome
Twins, Conjoined / pathology*
Ultrasonography, Doppler, Color
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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