Document Detail


Congenital varicella syndrome diagnosed by polymerase chain reaction--scarring of the spinal cord, not the skin.
MedLine Citation:
PMID:  10760023     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A term infant with congenital varicella syndrome (CVS) is reported. Monoplegia of the left arm and paraplegia were present with no evidence of dermatomal skin scarring. Following death at 12 days of age, autopsy documented severe atrophy and gliosis of the spinal cord. Testing for varicella-zoster virus by the polymerase chain reaction method on brain tissue was positive. This case extends the current understanding of the clinical and pathological features of CVS.
Authors:
C Cooper; J Wojtulewicz; V M Ratnamohan; S Arbuckle
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  36     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-08     Completed Date:  2000-05-08     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  186-8     Citation Subset:  IM    
Affiliation:
Departments of Neonatology and Pathology, Royal Alexandra Hospital for Children and Virology Unit ICPMR, Westmead Hospital, Westmead, New South Wales, Australia.
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MeSH Terms
Descriptor/Qualifier:
Chickenpox / congenital*,  diagnosis*,  pathology
Cicatrix / congenital*,  diagnosis*,  pathology
Female
Hand Deformities, Congenital / pathology
Humans
Infant, Newborn
Polymerase Chain Reaction
Skin / pathology
Spinal Cord / pathology*
Syndrome
Toes / abnormalities

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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