Document Detail

Congenital syphilis: unique clinical presentation in three preterm newborns.
MedLine Citation:
PMID:  15008395     Owner:  NLM     Status:  MEDLINE    
Three preterm newborns affected by congenital syphilis, born to mothers not adequately treated during pregnancy, are described. The clinical picture is characterized by a severe cholestatic hepatopathy and, in the two surviving patients, by an unusually wide ischemic-hemorrhagic lesion of the cerebral parenchyma. This lesion is probably due to a syphilitic endarteritis, and has rarely been described before in preterm infants.
Luca Filippi; Lisa Serafini; Carlo Dani; Giovanna Bertini; Marco Pezzati; Michele Tronchin; Firmino F Rubaltelli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  32     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2004  
Date Detail:
Created Date:  2004-03-10     Completed Date:  2004-04-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  90-4     Citation Subset:  IM    
Neonatal Intensive Care Unit, Department of Critical Care Medicine, University Careggi Hospital, Florence, Italy.
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MeSH Terms
Brain Ischemia / diagnosis,  etiology
Cerebral Hemorrhage / diagnosis,  etiology
Cholestasis, Intrahepatic / diagnosis,  etiology
Fatal Outcome
Gestational Age
Infant, Newborn
Infant, Premature*
Magnetic Resonance Imaging
Syphilis, Congenital / complications,  diagnosis*,  therapy

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