| Congenital rubella syndrome. How can we do better? | |
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MedLine Citation:
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PMID: 10463083 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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QUESTIONMy 22-year-old patient immigrated to Canada 6 years ago from a country where there are no routine immunizations. She is now at 10 weeks' gestation and was exposed to a child with rubella infection. Her immune status is unknown. Should I give her passive or active immunization? How should I follow her pregnancy? And what should I tell her about the risk for her fetus?ANSWERIf the exposure took place less than 1 week ago, blood should be sent for rubella antibody titre. If results are positive for IgG, she is immune and there is no risk for the fetus. If a patient's immune status is unknown and the time of exposure is uncertain, serum samples for rubella antibodies should be obtained 3 weeks apart. Detection of rubella-specific IgM in a sample will confirm recent infection. Your patient should be counseled about the potential risk for her fetus and referred to high-risk pregnancy clinic for follow up. If seroconversion does not take place, she requires immunization immediately postpartum before discharge from hospital. |
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Authors:
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B Bar-Oz; L Ford-Jones; G Koren |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Canadian family physician M?decin de famille canadien Volume: 45 ISSN: 0008-350X ISO Abbreviation: Can Fam Physician Publication Date: 1999 Aug |
Date Detail:
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Created Date: 1999-09-22 Completed Date: 1999-09-22 Revised Date: 2010-06-22 |
Medline Journal Info:
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Nlm Unique ID: 0120300 Medline TA: Can Fam Physician Country: CANADA |
Other Details:
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Languages: eng Pagination: 1865-9 Citation Subset: IM |
Affiliation:
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Division of Infections Dieases at the Hospital for Sick Children, Toronto. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Viral / blood Canada / epidemiology Emigration and Immigration Female Humans Immunoglobulin G / blood Immunoglobulin M / blood Pregnancy Pregnancy Complications, Infectious / blood, diagnosis, epidemiology, prevention & control* Rubella / blood, congenital*, diagnosis, epidemiology, prevention & control* Rubella virus / immunology Vaccination |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M |
| Comments/Corrections | |
Comment In:
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Can Fam Physician. 1999 Nov;45:2586, 2588
[PMID:
10587761
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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