| Congenital renal abnormalities in infants with in utero cocaine exposure. | |
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MedLine Citation:
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PMID: 2193169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the incidence of renal abnormalities among infants exposed to cocaine in utero, we performed ultrasound studies of the genitourinary tract in 100 consecutive infants admitted to the full-term nursery whose mothers had a history of cocaine use during pregnancy and/or a maternal toxicology screen was positive for cocaine. Mean gestational age of the newborns was 38.4 +/- 2.1 weeks. Mean birth weight was 2,846 +/- 561 gm.; 26% of the patients were less than 2,500 gm. and 18% were small for gestational age. Symptoms of drug withdrawal were present in 47 patients. Two newborns had murmurs consistent with a ventricular septal defect. On ultrasonography, 1 newborn had a unilateral multicystic/dysplastic kidney and 1 had kidneys that were 2 standard deviations below normal in size. Based on our results routine renal ultrasound studies do not appear to be indicated in full-term newborns exposed in utero to cocaine. |
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Authors:
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B J Rosenstein; J S Wheeler; P L Heid |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of urology Volume: 144 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1990 Jul |
Date Detail:
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Created Date: 1990-07-31 Completed Date: 1990-07-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 110-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, Maryland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced
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diagnosis*,
etiology,
pathology Adult Cocaine / adverse effects* Female Fetus / drug effects Humans Infant, Newborn Kidney / abnormalities* Neonatal Abstinence Syndrome / pathology Pregnancy Pregnancy Complications Substance-Related Disorders / complications Ultrasonography |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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