Document Detail

Congenital renal abnormalities in infants with in utero cocaine exposure.
MedLine Citation:
PMID:  2193169     Owner:  NLM     Status:  MEDLINE    
To determine the incidence of renal abnormalities among infants exposed to cocaine in utero, we performed ultrasound studies of the genitourinary tract in 100 consecutive infants admitted to the full-term nursery whose mothers had a history of cocaine use during pregnancy and/or a maternal toxicology screen was positive for cocaine. Mean gestational age of the newborns was 38.4 +/- 2.1 weeks. Mean birth weight was 2,846 +/- 561 gm.; 26% of the patients were less than 2,500 gm. and 18% were small for gestational age. Symptoms of drug withdrawal were present in 47 patients. Two newborns had murmurs consistent with a ventricular septal defect. On ultrasonography, 1 newborn had a unilateral multicystic/dysplastic kidney and 1 had kidneys that were 2 standard deviations below normal in size. Based on our results routine renal ultrasound studies do not appear to be indicated in full-term newborns exposed in utero to cocaine.
B J Rosenstein; J S Wheeler; P L Heid
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  144     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-07-31     Completed Date:  1990-07-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  110-2     Citation Subset:  AIM; IM    
Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
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MeSH Terms
Abnormalities, Drug-Induced / diagnosis*,  etiology,  pathology
Cocaine / adverse effects*
Fetus / drug effects
Infant, Newborn
Kidney / abnormalities*
Neonatal Abstinence Syndrome / pathology
Pregnancy Complications
Substance-Related Disorders / complications
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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