Document Detail


Congenital renal abnormalities in infants with in utero cocaine exposure.
MedLine Citation:
PMID:  2193169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the incidence of renal abnormalities among infants exposed to cocaine in utero, we performed ultrasound studies of the genitourinary tract in 100 consecutive infants admitted to the full-term nursery whose mothers had a history of cocaine use during pregnancy and/or a maternal toxicology screen was positive for cocaine. Mean gestational age of the newborns was 38.4 +/- 2.1 weeks. Mean birth weight was 2,846 +/- 561 gm.; 26% of the patients were less than 2,500 gm. and 18% were small for gestational age. Symptoms of drug withdrawal were present in 47 patients. Two newborns had murmurs consistent with a ventricular septal defect. On ultrasonography, 1 newborn had a unilateral multicystic/dysplastic kidney and 1 had kidneys that were 2 standard deviations below normal in size. Based on our results routine renal ultrasound studies do not appear to be indicated in full-term newborns exposed in utero to cocaine.
Authors:
B J Rosenstein; J S Wheeler; P L Heid
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  144     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-07-31     Completed Date:  1990-07-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  110-2     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced / diagnosis*,  etiology,  pathology
Adult
Cocaine / adverse effects*
Female
Fetus / drug effects
Humans
Infant, Newborn
Kidney / abnormalities*
Neonatal Abstinence Syndrome / pathology
Pregnancy
Pregnancy Complications
Substance-Related Disorders / complications
Ultrasonography
Chemical
Reg. No./Substance:
50-36-2/Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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