Document Detail

Congenital pulmonary vein stenosis: structural changes in a patient with normal pulmonary artery wedge pressure.
MedLine Citation:
PMID:  6690549     Owner:  NLM     Status:  MEDLINE    
A male infant is described who died at 13 months of age with stenosis of all extrapulmonary veins except the left upper vein. The pulmonary artery wedge pressure was normal, the first time this is reported in this condition. At autopsy, there were structural changes of the pulmonary arteries and veins in all lobes with or without pulmonary vein stenosis. Arterial changes-muscle extension, medial hypertrophy and decreased arterial size--analyzed quantitatively were found to be similar in all lobes. Venous medial hypertrophy was more marked in obstructed lobes. These anatomic changes are presumably due to fixed venous obstruction in the pulmonary lobes drained by stenotic veins and to high flow in the left upper lobe.
R L Geggel; R Fried; D T Tuuri; D C Fyler; L M Reid
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  3     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  193-9     Citation Subset:  IM    
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MeSH Terms
Constriction, Pathologic
Heart Catheterization
Hypertension, Pulmonary / pathology
Lung / pathology
Pulmonary Artery / pathology
Pulmonary Circulation
Pulmonary Veins / abnormalities*,  pathology
Pulmonary Wedge Pressure*
Grant Support

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