Document Detail


Congenital nephrotic syndrome responsive to captopril and indometacin.
MedLine Citation:
PMID:  10490532     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two children with congenital nephrotic syndrome are described (one with Finnish-type nephrosis, the other with diffuse mesangial sclerosis). Both children have had a prolonged and sustained clinical response with good physical health and normal growth patterns using captopril and indometacin as their sole treatment. No adverse effects have been noted. We recommend a trial of indometacin and captopril treatment in cases of congenital nephrotic syndrome.
Authors:
P A Heaton; O Smales; W Wong
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  81     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-18     Completed Date:  1999-10-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  174-5     Citation Subset:  AIM; IM    
Affiliation:
Taranaki Base Hospital, Private Bag 2016, New Plymouth 4620, New Zealand. paed.cacc@thcl.co.nz
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Captopril / therapeutic use*
Female
Humans
Indomethacin / therapeutic use*
Infant
Nephrotic Syndrome / congenital*,  drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Anti-Inflammatory Agents, Non-Steroidal; 53-86-1/Indomethacin; 62571-86-2/Captopril
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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