Document Detail

Congenital melanotic macules and Sebaceous Choristoma arising on the tongue of a newborn: epidermal choristoma?
MedLine Citation:
PMID:  15701089     Owner:  NLM     Status:  MEDLINE    
Oral hyperpigmentation is a common event in older individuals, however, is exceptional in neonates (congenital melanotic macules). Conversely, 70-80% of people have sebaceous glands in the oral mucosa, with the tongue representing an ectopic location and termed sebaceous choristoma by some authors. We report a case that fulfills both conditions in a tongue lesion. A 1-month-old boy presented with a pigmented macula on his tongue noted at birth. An excisional biopsy was performed showing a lesion lined by an epidermal-like epithelium with basal pigmentation, under which, sebaceous glands, abortive hair follicles and ductal structures mimicking apocrine glands were found. Seven cases of congenital melanotic macules of the tongue have been reported, however, none of them showed sebaceous glands under the lesion. Furthermore, there has not been a reported case of sebaceous choristoma of the tongue present at birth. We present a case that shares clinical and histological features of both conditions and propose the name 'epidermal choristoma'.
D Azorin; J Enriquez de Salamanca; I de Prada; I Colmenero; I Gonzalez Mediero
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  32     ISSN:  0303-6987     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-09     Completed Date:  2005-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Servicio de Anatomía Patológica, Hospital Infantil Universitario Niño Jesús, Madrid 28009, Spain.
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MeSH Terms
Choristoma / pathology*
Infant, Newborn
Melanosis / congenital,  pathology*,  surgery
Sebaceous Glands / pathology*,  surgery
Tongue Diseases / congenital,  pathology*,  surgery
Treatment Outcome

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