Document Detail

Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
MedLine Citation:
PMID:  168764     Owner:  NLM     Status:  MEDLINE    
A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth. She was born after a pregnancy complicated by exposure to multiple medications. This combination of malformations may represent a distinct entity unrelated to the medication or may be a complication of the intrauterine drug exposure.
C K Ho; R L Kaufman; W H McAlister
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  129     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  714-6     Citation Subset:  AIM; IM    
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MeSH Terms
Abnormalities, Drug-Induced / etiology*
Abnormalities, Multiple / chemically induced*
Chloramines / adverse effects
Chlorpromazine / adverse effects
Cleft Palate / chemically induced
Diphenoxylate / adverse effects
Estrogens, Conjugated (USP) / adverse effects
Heart Defects, Congenital / chemically induced
Hyperemesis Gravidarum / drug therapy
Infant, Newborn
Maternal-Fetal Exchange
Micrognathism / chemically induced
Mucopolysaccharidosis VI / chemically induced
Pregnancy Complications / chemically induced*
Prochlorperazine / adverse effects
Psychomotor Disorders / chemically induced
Vitamins / adverse effects
Reg. No./Substance:
0/Chloramines; 0/Estrogens, Conjugated (USP); 0/Vitamins; 50-53-3/Chlorpromazine; 58-38-8/Prochlorperazine; 915-30-0/Diphenoxylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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