Document Detail

Congenital malformation in newborns. Analysis of 501 cases.
MedLine Citation:
PMID:  7767849     Owner:  NLM     Status:  MEDLINE    
Over a 14-year period in Chang Gung Memorial Hospital, 510 out of 44, 362 newborns were found to have birth defects. Maternal age, gestational age, parity, infant sex and birth weight were analyzed for each anomaly and compared to normal newborns. The average maternal age and parity for newborns with congenital anomalies were not significantly different from normal newborns. Mothers giving birth to babies with chromosomal aberrations, however, had a significantly older maternal age than the normal population. The gestational age at delivery was significantly shorter for all except craniofacial anomaly. In addition, there was a high percentage of intrauterine growth retardation in congenital anomalies. The central nervous system, the musculoskeletal system and craniofacial systems were the most commonly involved. The leading anomalies included cleft lip, cleft palate, anencephaly, polydactyly, hydrops fetalis, trisomy 21 and cystic hygroma. With improved ultrasound equipment and other prenatal diagnostic procedures, many defects of the fetus can now be identified. If the fetus is diagnosed with a surgically correctable lesion like cleft lip, it can be kept to term, delivered, then managed postnatally. If life-incompatible malformations have been detected before the 24th week, physicians are in a good position to counsel the parents. After the 24th week termination is proscribed by law. Therefore, physicians must take special care to detect fetal abnormalities early.
T T Hsieh; L M Lo; J J Hsu; T H Chiu; J D Liou; C C Hsieh; T C Chang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital     Volume:  18     ISSN:  -     ISO Abbreviation:  Changgeng Yi Xue Za Zhi     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-06-30     Completed Date:  1995-06-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9809559     Medline TA:  Changgeng Yi Xue Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  14-9     Citation Subset:  IM    
Division of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
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MeSH Terms
Congenital Abnormalities / diagnosis*,  epidemiology
Fetal Diseases / diagnosis*
Gestational Age
Infant, Newborn
Maternal Age
Prenatal Diagnosis*
Risk Factors
Taiwan / epidemiology

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