Document Detail

Congenital limb deficiency: maternal factors in pregnancy.
MedLine Citation:
PMID:  3469993     Owner:  NLM     Status:  MEDLINE    
Maternal factors in pregnancy were examined in a case-control study of 155 children with limb deficiencies (longitudinal and transverse) born 1970-1981 inclusive and 274 matched normal controls. Vomiting of pregnancy was associated with an increased risk of longitudinal limb reduction defects. Gestational bleeding has long been known for its association with perinatal mortality, low birth-weight and prematurity; limb deficiencies have also been noted. In the present study the pattern of bleeding differed between women in the transverse and longitudinal groups, with the possibility of a causal role for bleeding in the aetiology of longitudinal but not transverse defects. There was a significant statistical risk associated with respiratory infections comparable with the reported association of congenital limb deficiency and influenza from Finland.
A Kricker; J Elliott; J Forrest; J McCredie
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  26     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1987-04-23     Completed Date:  1987-04-23     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  272-5     Citation Subset:  IM    
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MeSH Terms
Infant, Newborn
Limb Deformities, Congenital*
Longitudinal Studies
Pregnancy Complications*
Respiratory Tract Diseases*
Uterine Hemorrhage*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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