Document Detail


Congenital hypothyroidism in Young-Simpson syndrome.
MedLine Citation:
PMID:  19189705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a patient with the clinical spectrum of Young-Simpson syndrome. This rare genetic disorder is characterized by congenital hypothyroidism, mental retardation and blepharophimosis. Young-Simpson syndrome is, at present, poorly known to endocrinologists and pediatricians, and should be included in the differential diagnosis of congenital hypothyroidism. It is important to underline that the association of congenital hypothyroidism, blepharophimosis and ptosis allows an exact clinical diagnosis, since the majority of other clinical aspects are common to other disorders.
Authors:
S Stagi; G Bindi; E Lapi; M L Giovannucci-Uzielli; R Salti; F Chiarelli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  21     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2009-02-04     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  1089-92     Citation Subset:  IM    
Affiliation:
Paediatric Endocrinology Unit, Department of Paediatrics, University of Florence, A. Meyer Children's Hospital, Florence, Italy. stefano.stagi@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / pathology*
Blepharophimosis / pathology*
Child, Preschool
Congenital Hypothyroidism / diagnosis*
Facial Bones / abnormalities
Facies
Humans
Male
Mental Retardation / pathology*
Syndrome
Thyroid Gland / pathology,  radionuclide imaging,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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