Document Detail

Congenital hypofibrinogenemia and pregnancy, obstetric and hematological management.
MedLine Citation:
PMID:  3428714     Owner:  NLM     Status:  MEDLINE    
A 27-year-old pregnant woman with severe congenital hypofibrinogenemia was studied from the 18th to the 40th week of pregnancy, after which she had a normal delivery. The results of the quantitative and qualitative fibrinogen studies done on the patient made it possible to rule out associated dysfibrinogenemia. No variations in the concentration and function of fibrinogen were observed during gestation. The only treatment given was a transfusion of fresh plasma prior to delivery. The importance of fibrinogen in maintaining normal placental insertion and the obstetric management of predelivery and delivery are discussed.
J Gilabert; E Regañon; V Vila; A Baamonde; P Villa; J Aznar; M Galbis
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  24     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1987  
Date Detail:
Created Date:  1988-02-26     Completed Date:  1988-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  271-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Hospital La Fe, Valencia, Spain.
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MeSH Terms
Afibrinogenemia / complications*
Blood Coagulation Tests
Blood Proteins / metabolism
Fibrinogen / metabolism
Pregnancy Complications / blood*
Reg. No./Substance:
0/Blood Proteins; 9001-32-5/Fibrinogen

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