Document Detail


Congenital hypo- and hypermyelination neuropathy. Two cases.
MedLine Citation:
PMID:  3673511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two young patients were referred recently to the authors for investigation of a peroneal atrophy syndrome. Since the first symptoms were observed in infancy, a congenital hypomyelination neuropathy was suspected, and superficial peroneal nerve biopsies were taken. Signs of severe and widespread demyelination/remyelination were observed. These features appeared morphologically similar to those observed in the globular or tomaculous neuropathies. The mechanism of the hypermyelination is discussed.
Authors:
J M Vallat; R Gil; M J Leboutet; J Hugon; D Moulies
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neuropathologica     Volume:  74     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-12-07     Completed Date:  1987-12-07     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  197-201     Citation Subset:  IM    
Affiliation:
Department of Neurology, University Hospital, Limoges, France.
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Demyelinating Diseases / congenital*,  pathology
Female
Humans
Male
Microscopy, Electron
Myelin Sheath / pathology*,  ultrastructure
Nervous System Diseases / congenital*,  pathology

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