| Congenital herpes infection: placental and umbilical cord findings. | |
| | |
MedLine Citation:
|
PMID: 8385765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Herpes simplex virus (HSV) fetal infections are rare, and the routes through which the virus reaches the fetus are insufficiently documented. CASE: We describe a case of congenital HSV ascending infection in an infant whose membranes were intact until cesarean delivery. The pathologic findings were remarkable for a mild lymphoplasmocytic funisitis and the presence of positive viral staining of cells in the subamniotic connective tissue, amniotic epithelium, and umbilical cord. Antigen-positive cells within the extraplacental membranes were mostly located in an area presumably adjacent to the cervix before birth. In the umbilical cord, positive viral staining was confined to cells in the subamniotic mesenchyma away from the perivascular mesenchyma of the central portion of the cord. CONCLUSION: Immunohistochemistry using herpes-specific antibodies, coupled with routine histologic examination, allows early diagnosis of congenital HSV infection and documentation of the ascending route of infection when the membranes are intact. |
| | |
Authors:
|
S R Hyde; G P Giacoia |
Related Documents
:
|
9780205 - Virus-induced immunoinflammatory lesions in the absence of viral antigen recognition. 1653415 - Analysis of herpes simplex virus-induced mrna destabilizing activity using an in vitro ... 3169755 - Tzanck smear in diagnosing genital herpes. 2835355 - Increased adherence of human granulocytes to herpes simplex virus type 1 infected endot... 12548205 - Genital tract and plasma human immunodeficiency virus viral load throughout the menstru... 8289015 - Undifferentiated carcinoma with lymphoid stroma of the parotid gland. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 81 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1993 May |
Date Detail:
|
Created Date: 1993-05-13 Completed Date: 1993-05-13 Revised Date: 2009-10-26 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 852-5 Citation Subset: AIM; IM |
Affiliation:
|
Department of Pathology, Saint Francis Hospital, Tulsa, Oklahoma. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Cesarean Section* Extraembryonic Membranes / microbiology Female Herpes Simplex / congenital*, diagnosis Humans Immunoenzyme Techniques Infant, Newborn Placenta / microbiology* Pregnancy Pregnancy Complications, Infectious / diagnosis* Simplexvirus / isolation & purification* Umbilical Cord / microbiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Müllerian adenosarcoma presenting as cervical polyps: a report of seven cases and review of the lit...
Next Document: Modern diet for patients with hyperlipoproteinemia